Prepare the Jalapeños:

Preheat your oven to 400°F (200°C).
Halve the jalapeños lengthwise and remove the seeds and membranes. If you're sensitive to heat, wear gloves to avoid irritation.

Make the Filling:

In a bowl, mix together the cream cheese, shredded cheese, garlic powder, onion powder, salt, and pepper until well combined.

Stuff the Jalapeños:

Spoon the cheese mixture into each jalapeño half, filling them generously.

Bread the Poppers:

Dip each stuffed jalapeño first into the milk, then dredge in flour, dip back into the milk, and finally coat with breadcrumbs.
Bake:

Bake:

Place the breaded jalapeño poppers on a greased baking sheet. Lightly spray or brush the poppers with oil.
Bake in the preheated oven for about 20-25 minutes or until the poppers are golden brown and crispy.

Serve:

Allow the poppers to cool slightly before serving. They can be enjoyed on their own or with a dipping sauce like ranch dressing or sour cream.